The Complete OF·27 System
The full OF·27 Protocol in one order: reset the scalp once or twice a week, signal the follicle every night. Everything the twelve-week protocol requires, as studied.
The Complete OF·27 System
The full OF·27 Protocol in one order: reset the scalp once or twice a week, signal the follicle every night. Everything the twelve-week protocol requires, as studied.
Your Follicular Serum rate locks at $175/bottle for life. Reserve the Complete System now and every future order keeps that rate. After the founding batch, the standard rate is $255.
Complete System orders carry the guarantee. Email a baseline photo to contact@of27bioscience.com within 7 days of delivery, run the full twelve-week course, and if week 12 shows no measurable change, we refund the course. Full conditions in the refund policy.
Why the complete system
The OF·27 Protocol runs both phases in parallel from day one: Phase 1 keeps the scalp clear and calm once or twice a week, Phase 2 delivers its growth-factor signal every night, and the written guide tells you exactly how and when. The published +33.5% was measured over twelve weeks of the full protocol.
What's in the box
One 30 mL bottle of OF·27 Scalp Reset Serum (Phase 1), two 50 mL bottles of OF·27 Follicular Serum (Phase 2, the full 12-week course at one pump nightly, six weeks per bottle), and the OF·27 Protocol, a written guide covering both phases.
Composition — Follicular Serum (Phase 2)
An aqueous formulation built around two recombinant fibroblast growth factors, FGF·2 and FGF·7, fused to a plant-derived oleosome carrier for stability and delivery. Everything else in the bottle is there to support them.
- FGF·2: 100 ng/mL (0.0005%) · hero active
- FGF·7: 500 ng/mL (0.0025%) · hero active
- Carrier: oleosome-protein fusion, from Camelina sativa
- Support actives: panthenol (pro-vitamin B5), niacinamide (vitamin B3), adenosine · scalp comfort and conditioning
- Humectants: glycerin 4%, trehalose 3%
- Preservation: propanediol, 1,2-hexanediol, caprylhydroxamic acid (≤ 2% total)
- Texture: xanthan gum 0.3%
- pH: 5.8 ± 0.2 at 25°C
- Storage: refrigeration recommended (2–8 °C); do not freeze
Not in the formulation: fragrance, silicones, animal-derived inputs.
Full ingredient list (INCI): Aqua, Glycerin, Trehalose, Propanediol, Panthenol, Niacinamide, Xanthan Gum, Adenosine, 1,2-Hexanediol, Caprylhydroxamic Acid, sr-Camelina Sativa Oleosin-1 sh-Polypeptide-3, sr-Camelina Sativa Oleosin-1 sh-Polypeptide-1.
Composition — Scalp Reset Serum (Phase 1)
A pH-adjusted lactic-acid exfoliating serum. Lactic acid clears buildup and dead surface cells; sodium hyaluronate and glycerin hold water at the surface; nettle leaf extract calms an oily, irritated scalp. No fragrance, no silicones.
Full ingredient list (INCI): Aqua (Water), Lactic Acid, Pentylene Glycol, Potassium Hydroxide, Butylene Glycol, Glycerin, Sodium Hyaluronate, Urtica Dioica (Nettle) Leaf Extract.
How it's scheduled
Run both phases from day one, each on its own schedule: Scalp Reset once or twice a week (applied to a dry scalp, left on 3–5 minutes, then rinsed), the Follicular Serum one pump nightly for the full 12-week course. The Protocol covers the details.
Shipping
The Scalp Reset Serum ships now; the Follicular Serum bottles ship with the founding batch mid-October, in order of reservation. You receive tracking for each shipment.
What participants reported after twelve weeks. Self-assessment questionnaire, active arm (n=20), from the independent study conducted on the active. Published in full, including the mixed results.
Individual accounts, reproduced as written. Individual results vary; the controlled data above is the standard we hold ourselves to.
“I used OF·27 every night for six weeks and found it very easy to stay consistent with. The serum is lightweight, absorbs quickly, and does not leave my roots greasy. By the end of the first bottle, I was seeing noticeably less hair in the shower and several short new hairs around my hairline. The results developed gradually, but the overall improvement was clearer than I expected after one bottle.”
“After several weeks of regular use, the thinner areas around my temples looked less exposed and my hairline appeared more even. I could also see a number of fine new hairs coming through. They are still developing, so I would not call the result complete, but the difference is already visible and encouraging.”
“My main concern was increased daily shedding. After approximately two weeks, I began noticing fewer hairs on my brush and in the shower. By the end of the sixth week, the reduction was consistent and easy to notice. My overall density also looks slightly improved, particularly around the front.”
“OF·27 feels more like a high-quality skincare serum than a conventional hair treatment. It spreads easily, absorbs without residue, and has not caused any irritation or flaking. I have also noticed less shedding and more short hairs around the thinner areas. The changes are progressive, but the serum has already delivered enough improvement for me to keep using it.”
“I took photographs before starting and again after six weeks. Day to day, the changes were gradual, but the side-by-side comparison showed a real difference. My parting looks narrower, the scalp is less visible, and there are more fine hairs along the front. It is not an overnight transformation, but the progress is more noticeable than I initially realised.”
“After finishing my first bottle, I noticed small new hairs around my temples and less scalp showing under bright lighting. The overall appearance of my hair is fuller and healthier. The new hairs are still fine and will need time to mature, but these are the strongest early results I have seen from a topical serum.”
“I have a sensitive scalp, so I was pleased that OF·27 caused no noticeable redness, itching, or dryness. It dries quickly and does not make my hair look oily, even with nightly application. I have seen a clear reduction in shedding and early regrowth around my hairline. Density changes are still developing, but the direction is very positive.”
“The crown was the area I was most concerned about. After consistent use, it looks less transparent in photographs and under overhead lighting. The area has not completely filled in, but the overall coverage is visibly better and my hair sits more naturally over the scalp. The improvement has been gradual but convincing.”
“OF·27 did not produce an overnight change, but the improvements appeared in a logical progression. I first noticed less shedding, followed by short new hairs and then a fuller overall appearance. After six weeks, my hair looks healthier and the thinner areas are less noticeable. Consistency is important, but the results have made the routine worthwhile.”
“I followed the recommended routine of one pump each night before bed. The airless packaging makes the serum easy to dose, and the formula fits into my routine without affecting styling. After six weeks, my hairline looks fuller, shedding has decreased, and I can see fine regrowth in several thinner areas. I expect the results to continue developing over the full twelve-week course, but the first bottle has already been very positive.”