Noticing thinning hair? Answer 10 quick questions and get a 12-week hair routine built for you
Are you a woman or a man?
How old are you?
Where is your hair thinning? Choose all that apply.
Where is your hair thinning? Choose all that apply.
You are not alone
About 4 in 10 women have thinner hair by age 50
0 in 10
women have thinner hair by age 50
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It starts slowly
Each new hair grows back a little thinner. It takes months to notice. You noticed {problem_areas} early, while most of your follicles are still active.
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It has a known cause
Follicles slow down when the growth signals they need get weaker. This happens after having a baby, during perimenopause, and after long periods of stress.
You are not alone
Up to 5 in 10 men lose noticeable hair in their lifetime
0 in 10
men lose noticeable hair in their lifetime
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It starts slowly
Your hairline or crown moves back a little with every hair growth cycle. It hides for months, then shows up in one photo. You noticed {problem_areas} early.
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It has a known cause
The follicles at your temples and crown are the most sensitive to weak growth signals. The routine you will see works on that signal, on your scalp. Nothing to swallow.
How long ago did you first notice it?
Did any of these happen to you in the last 2 years? Choose all that apply.
When do you notice it most?
When do you notice it most?
What this means
A wider part is the first sign of thinning hair. It is also the easiest one to track.
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Why your part shows it first
Each hair grows back a little thinner, so more scalp shows through. A photo from above catches this long before the mirror does.
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Why that helps you
Take one photo of your part on day one. Take the same photo at week 12, same light, same distance. Then compare the two.
What this means
Men lose hair at the temples and crown first. Here is why.
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Why the temples and crown
The follicles there are the most sensitive to the signals that tell hair to keep growing. When those signals fade, the hair grows back thinner and shorter each cycle. That is the line you see moving back.
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Why timing matters
Most men wait until everyone can see it. A 12-week routine with a photo at the start and one at the end tells you in one season if it is working.
What this means
Hair loss happens slowly. A photo is the only way to see it clearly.
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Why you don't notice it
Hair changes a little with every growth cycle. Day to day it looks the same. Month to month it does not.
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How to track it
Take a photo of your scalp on day one. Take the same photo at week 12 under the same light. Compare the two.
Do any of these apply to you right now? Choose all that apply.
Do any of these apply to you right now? Choose all that apply.
What have you already tried for your hair? Choose all that apply.
Why it didn't work
Most hair products feed the follicle or clean the scalp. Neither one tells the follicle to grow.
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Feeding
Supplements and gummies feed the follicle from inside. That helps a hungry follicle. It does nothing for a follicle that stopped getting the signal to grow.
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Cleaning
Oils, rinses and most serums work on the surface of the scalp. Good for the scalp. Still no signal reaches the root.
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Sending the signal
The routine you are about to see puts the growth signal itself on your scalp, where the follicle can read it. One pump every night for 12 weeks.
Starting fresh
You haven't tried anything yet. Here is what most people waste money on first.
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Feeding
Supplements and gummies feed the follicle from inside. That helps a hungry follicle. It does nothing for a follicle that stopped getting the signal to grow.
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Cleaning
Oils, rinses and most serums work on the surface of the scalp. Good for the scalp. Still no signal reaches the root.
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Sending the signal
The routine you are about to see puts the growth signal itself on your scalp, where the follicle can read it. One pump every night for 12 weeks.
How hair grows
Your follicles need a signal to grow hair. Most products never send it.
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The signal
Each follicle waits for a signal to start growing and another to keep going. When the signals get weaker, the follicle still makes hair, but thinner and shorter every cycle. That is the thinning you see.
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What supplements and rinses do
A supplement feeds the follicle. A rinse cleans the scalp. Both help. Neither one sends the signal.
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What this routine does
It puts the growth signal on your scalp. One pump every night for 12 weeks.
The study
In an independent 12-week study, 90% of people using the active ingredient had denser hair. 35% on the placebo did.
0%
Used the active ingredient for 12 weeks
Used a placebo
0%
of people whose hair density improved by week 12
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Who was in it
40 women with shedding-prone hair. 84 days. An independent lab. Published in 2026.
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What changed
Hair density in the active group went up 33.5% from where it started. It was already higher by day 28 and stayed up through week 12.
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What it means for you
Your routine uses the same active ingredient. Your own day-one photo next to your week-12 photo will show you what it did.
What do you NOT want in a hair routine? Choose all that apply.
What matters most to you in a hair routine? Pick one.
What matters most to you in a hair routine? Pick one.
Could you put one pump on your scalp every night?
Building your hair routine
- Matching your answers to a 12-week plan
- Setting your review date
- Preparing your day-one photo guide
Week 12Honestly didn't expect much. But around week 5 I noticed way less hair in the drain. Then my husband pointed out new little hairs coming in at my hairline. That's when I knew it was actually working.
Week 12The temples were the worst part for me. About six weeks in, they just looked less see-through. Like actual coverage came back. Subtle but real.
Week 12My part used to look wide enough to land a plane on. It's tighter now, less scalp showing. And there's a bunch of fine new hairs along the front I definitely didn't have before.
I followed the routine of one pump each night before bed. My hairline looks fuller and the thinner areas look denser than when I started.
Your routine
Your routine: one pump on your scalp every night. No hormones, no pills.
You wanted a way forward that leaves your hormones alone. This one goes on your scalp, one pump at night, and carries two growth factors in the same class your follicles already respond to. There's no pill in it and nothing to take by mouth.
What the twelve weeks look like
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Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
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Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
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Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: one pump on your scalp at night. That is the whole daily step.
You wanted less hassle. This is one pump on the scalp before bed and a two-minute rinse once or twice a week. Each bottle lasts six weeks, and two bottles cover the whole course, so there is nothing to reorder halfway.
What the twelve weeks look like
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Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
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Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
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Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: the evidence first, and a straight answer about men
You wanted more than a claim on a bottle. Both growth factors are named on the label with their amounts, and the twelve-week study behind the active is published with a placebo arm. That study enrolled women, and a men's study is next on the company's list. Until then, your own two photos are the evidence that counts.
What the twelve weeks look like
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Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: 12 weeks, with a photo of your hairline at the start and at the end
You wanted to see the change at your hairline or crown without relying on memory. Your course starts with one photo under a light you can use again and ends with the same photo at week twelve. In between, one pump every night.
What the twelve weeks look like
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Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: 12 weeks, with a photo of your part at the start and at the end
You wanted your part to look fuller in photos and your ponytail to feel like yours again. Your course starts with one overhead photo of your part and ends with the same photo at week twelve, with one pump on the scalp every night in between.
What the twelve weeks look like
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Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: a 12-week course for shedding, with a set date to judge it
You wanted to stop counting hairs in the brush. Shedding-prone hair is exactly what the twelve-week study enrolled, and the routine gives you a set course with a photo at each end, so you judge it on a date rather than on a bad hair day.
What the twelve weeks look like
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Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: one pump on your scalp every night. No hormones.
You wanted fuller-looking hair without touching your hormones. This routine goes on your scalp, not in your body: one pump at night carrying two growth factors, plus a weekly rinse that clears the way for them.
What the twelve weeks look like
-
Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: one pump on your scalp at night. That is the whole daily step.
You wanted a plan you could follow without adding another shelf of products. This is one pump on the scalp at night and a two-minute rinse once or twice a week. The written guide covers both, and two bottles cover the full twelve weeks.
What the twelve weeks look like
-
Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: the evidence first, then you decide
You wanted to know what you're paying for before you pay. Both growth factors are named on the label with their amounts, the twelve-week study behind the active was placebo-controlled and published, and the course ends with a photo comparison you take yourself.
What the twelve weeks look like
-
Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: the full price and the refund terms up front
You wanted the numbers before anything else. Both serum bottles, the scalp rinse and the guide come in one order, paid once, with no repeat charge. The price and every refund term are on the next page, before you decide.
What the twelve weeks look like
-
Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
Your routine
Your routine: private, at home, on your own schedule
You wanted to handle this at home, without a clinic chair or a pharmacy counter. One pump on your scalp at night and a rinse once or twice a week, delivered in one box, with two photos only you will ever see.
What the twelve weeks look like
-
Weeks 1 to 6, bottle one
One pump every night. Some extra shedding early on is normal as resting hairs make room for new growth.
-
Weeks 7 to 12, bottle two
Same routine, same rinse. Density in the study was already above its starting point at day 28 and held through week twelve.
-
Week 12
Take the matching photo and put the two side by side.
You said you don't want these. Here is how the routine handles each one
Your result is built around {priority}. The next page shows the exact routine, what it costs, and the refund terms before you decide.
The OF·27 Hair Protocol
Built for what you told us: {problem_areas}, and {priority} as the thing that matters most.
- Growth Factors FGF·2 & 7, Oleosome delivery
- Backed by a placebo-controlled clinical study
- Drug-free, fragrance-free, leave-on
This feels nothing like the treatments I've tried before. My hair looks fuller and thicker for the first time in years.
Is this a drug?
When would I see a change?
How do I use it?
When does it ship, and can I cancel?
What's in your order
Two serums that work as a pair, and a short guide that tells you exactly what to do.
A rinse-off exfoliating treatment. It clears buildup and excess oil so the scalp is clean and calm before the nightly serum goes on.
One pump on the scalp before bed. Leave it on. One 50 mL bottle lasts 6 weeks, so the two bottles in the Advanced Protocol cover the full 12 weeks.
FGF·2, oleosome-fused
FGF·7, oleosome-fused
A short PDF, emailed the moment you order: how to use both serums, when to open the second bottle, and how to take your two photos for the guarantee.
Fuller-looking hair in 12 weeks.
One pump a night. +33.5% hair density in the 12-week study of the active.
- 2 Follicular Serums, the full 12 weeks
- Scalp Reset Serum, the weekly prepIncluded
$79 - The written guide, emailed todayIncluded
Next batch ships mid-October and it's already:
See a difference in 12 weeks, or your money back.
Use the Advanced Protocol every night for 12 weeks. Take a photo of your parting when the box arrives and another at week 12. If you can't see a difference between the two, we refund you.
Independent clinical study: measured over 12 weeks, against a placebo.
An independent laboratory tested the active in OF·27 on 40 women for 12 weeks, half of them on a placebo. Here is what they measured.
Tap a result to see the detail
Study of the active, Abich S.r.l., Italy, 2026, funded by the active's maker. Individual results vary.
Hair density33.5% more hairs per cm² at week 12 than at the start. The placebo group: +7.2%, not significant.
Hairs in the growth phaseAnagen to telogen ratio, compared with the placebo group.
Hair thicknessShaft diameter at week 12, compared with the start.
Scalp hydrationCompared with the placebo group at week 12.
What customers say
In their own words. Nobody was paid for an opinion.
I took photographs before starting and again at the end. Day to day, the changes were gradual, but the side-by-side comparison showed a real difference. My parting looks narrower, the scalp is less visible, and the hair along the front looks fuller. It is not an overnight transformation, but the progress is more noticeable than I initially realised.
I used OF·27 every night and found it very easy to stay consistent with. The serum is lightweight, absorbs quickly, and does not leave my roots greasy. By the end, my hair looked and felt fuller around the hairline. The results developed gradually, but the overall improvement was clearer than I expected.
The crown was the area I was most concerned about. After consistent use, it looks less transparent in photographs and under overhead lighting. The change is not total, but the overall coverage looks visibly better and my hair sits more naturally over the scalp. The improvement has been gradual but convincing.
Individual experiences of how their hair looked and felt, not what you should expect. Results range from no change to visible change. OF·27 is marketed as a cosmetic and is not intended to diagnose, treat, cure or prevent any disease.
Questions
Which protocol should I choose?
The duration measured in the study is 12 weeks, one pump nightly, and one 50 mL bottle covers six weeks. The Advanced Protocol covers the full 12 weeks, includes the Scalp Reset Serum and the written guide at no extra charge, and carries the money-back guarantee; the Standard Protocol covers the first six weeks with a single bottle and gives you a chance to try the product.
What arrives, and when?
On the Advanced Protocol, the written guide arrives by email today; the serums ship together in one shipment with the next batch in mid-October, in order of reservation. The Standard Protocol is one bottle, shipped the same way. Nothing else ships at purchase.
Why do I pay now if it ships in October?
OF·27 is a refrigerated protein formulation bottled to reservations in one small run, so nothing is warehoused. Your payment reserves an allocation at the pre-order price and fixes your place in the dispatch order. You can cancel for a full refund at any time before dispatch.
What does the Scalp Reset Serum do?
It prepares the scalp: a rinse-off exfoliating treatment that removes buildup and excess oil and rebalances the scalp, so the nightly serum is applied to a clean, prepared scalp. The measured result comes from the study of the active, applied nightly across 12 weeks. The Scalp Reset Serum is included with the Advanced Protocol.
When would I expect to see a change?
In the study, the measurements were taken at week 12. Photograph your scalp before the first application and again at week 12, in the same light; that comparison is also what the guarantee is assessed on. We cannot predict an individual result.
What if nothing changes?
Advanced Protocol orders carry the money-back guarantee. Email a baseline photograph to contact@of27bioscience.com within seven days of delivery, run the full 12 weeks as directed, and send a matched photograph at week 12. If we cannot see a visible difference between the two, we refund the product price; shipping, duties and taxes are not refunded. Claims open between the end of week 12 and the end of week 14; one claim per customer, on a first order placed directly on of27bioscience.com. Full conditions.
Is this a drug?
OF·27 is marketed as a cosmetic and is not intended to diagnose, treat, cure or prevent any disease. It is a topical built around two fibroblast growth factors, FGF·2 and FGF·7, carried in a plant-derived oleosome, and it is not a prescription product. If you already use a prescription treatment, speak to your prescriber before adding anything.
What happens after week 12?
The study ran twelve weeks; we have no data on what happens after week 12, with or without continued use, and we will not guess. If you choose to continue, one bottle covers six weeks.
Fuller-looking hair in 12 weeks.
One pump a night. +33.5% hair density in the 12-week study of the active.
- 2 Follicular Serums, the full 12 weeks
- Scalp Reset Serum, the weekly prepIncluded
$79 - The written guide, emailed todayIncluded
Next batch ships mid-October and it's already:
I followed the recommended routine of one pump each night before bed. The airless bottle makes the serum easy to dose, and the formula fits into my routine without affecting styling. My hairline looks fuller and the thinner areas look denser than when I started. The experience has been very positive.