The OF·27 Hair Protocol
Growth factors FGF·2 and FGF·7, oleosome-delivered to the scalp so they arrive intact. Backed by an independent, placebo-controlled study: +33.5% hair density at week 12.
- Growth Factors FGF·2 & 7, Oleosome delivery
- Backed by a placebo-controlled clinical study
- Drug-free, fragrance-free, leave-on
This feels nothing like the treatments I've tried before. My hair looks fuller and thicker for the first time in years.
Is this a drug?
When would I see a change?
How do I use it?
When does it ship, and can I cancel?
What's in your order
Two serums that work as a pair, and a short guide that tells you exactly what to do.
A rinse-off exfoliating treatment. It clears buildup and excess oil so the scalp is clean and calm before the nightly serum goes on.
One pump on the scalp before bed. Leave it on. One 50 mL bottle lasts 6 weeks, so the two bottles in the Advanced Protocol cover the full 12 weeks.
FGF·2, oleosome-fused
FGF·7, oleosome-fused
A short PDF, emailed the moment you order: how to use both serums, when to open the second bottle, and how to take your two photos for the guarantee.
Independent clinical study: measured over 12 weeks, against a placebo.
An independent laboratory tested the active in OF·27 on 40 women for 12 weeks, half of them on a placebo. Here is what they measured.
Study of the active, Abich S.r.l., Italy, 2026, funded by the active's maker. Individual results vary.
Hair density33.5% more hairs per cm² at week 12 than at the start. The placebo group: +7.2%, not significant.
Hairs in the growth phaseAnagen to telogen ratio, compared with the placebo group.
Hair thicknessShaft diameter at week 12, compared with the start.
Scalp hydrationCompared with the placebo group at week 12.
What customers say
In their own words. Nobody was paid for an opinion.
I took photographs before starting and again at the end. Day to day, the changes were gradual, but the side-by-side comparison showed a real difference. My parting looks narrower, the scalp is less visible, and the hair along the front looks fuller. It is not an overnight transformation, but the progress is more noticeable than I initially realised.
I used OF·27 every night and found it very easy to stay consistent with. The serum is lightweight, absorbs quickly, and does not leave my roots greasy. By the end, my hair looked and felt fuller around the hairline. The results developed gradually, but the overall improvement was clearer than I expected.
The crown was the area I was most concerned about. After consistent use, it looks less transparent in photographs and under overhead lighting. The change is not total, but the overall coverage looks visibly better and my hair sits more naturally over the scalp. The improvement has been gradual but convincing.
Questions
Which protocol should I choose?
The duration measured in the study is 12 weeks, one pump nightly, and one 50 mL bottle covers six weeks. The Advanced Protocol covers the full 12 weeks, includes the Scalp Reset Serum and the written guide at no extra charge, and carries the money-back guarantee; the Standard Protocol covers the first six weeks with a single bottle and gives you a chance to try the product.
What arrives, and when?
On the Advanced Protocol, the written guide arrives by email today; the serums ship together in one shipment with the next batch in mid-October, in order of reservation. The Standard Protocol is one bottle, shipped the same way. Nothing else ships at purchase.
Why do I pay now if it ships in October?
OF·27 is a refrigerated protein formulation bottled to reservations in one small run, so nothing is warehoused. Your payment reserves an allocation at the pre-order price and fixes your place in the dispatch order. You can cancel for a full refund at any time before dispatch.
What does the Scalp Reset Serum do?
It prepares the scalp: a rinse-off exfoliating treatment that removes buildup and excess oil and rebalances the scalp, so the nightly serum is applied to a clean, prepared scalp. The measured result comes from the study of the active, applied nightly across 12 weeks. The Scalp Reset Serum is included with the Advanced Protocol.
When would I expect to see a change?
In the study, the measurements were taken at week 12. Photograph your scalp before the first application and again at week 12, in the same light; that comparison is also what the guarantee is assessed on. We cannot predict an individual result.
What if nothing changes?
Advanced Protocol orders carry the money-back guarantee. Email a baseline photograph to contact@of27bioscience.com within seven days of delivery, run the full 12 weeks as directed, and send a matched photograph at week 12. If we cannot see a visible difference between the two, we refund the product price; shipping, duties and taxes are not refunded. Claims open between the end of week 12 and the end of week 14; one claim per customer, on a first order placed directly on of27bioscience.com. Full conditions.
Is this a drug?
OF·27 is marketed as a cosmetic and is not intended to diagnose, treat, cure or prevent any disease. It is a topical built around two fibroblast growth factors, FGF·2 and FGF·7, carried in a plant-derived oleosome, and it is not a prescription product. If you already use a prescription treatment, speak to your prescriber before adding anything.
What happens after week 12?
The study ran twelve weeks; we have no data on what happens after week 12, with or without continued use, and we will not guess. If you choose to continue, one bottle covers six weeks.
The OF·27 Hair Protocol
Growth factors FGF·2 and FGF·7, oleosome-delivered to the scalp so they arrive intact. Backed by an independent, placebo-controlled study: +33.5% hair density at week 12.
- Growth Factors FGF·2 & 7, Oleosome delivery
- Backed by a placebo-controlled clinical study
- Drug-free, fragrance-free, leave-on
This feels nothing like the treatments I've tried before. My hair looks fuller and thicker for the first time in years.