OF·27 — the protocol · 3-bottle pack
OF·27 — the full twelve-week protocol. Three 50 mL airless pump bottles, one for each four-week course, completing the course on which the published endpoint was measured. The recommended way to run the protocol; single bottles remain available for a four-week course.
It is formulated with two fibroblast growth factors, FGF·2 and FGF·7. The active is supplied by Core Biogenesis, a French biotechnology company, and stabilised in a Camelina sativa oleosome carrier. Two pumps to the scalp, morning and evening; one bottle lasts four weeks.
Cited measurement
OF·27 cites an independent, randomised, single-blind, placebo-controlled study conducted on the active (n=40, twelve weeks): C-CUBE-quantified hair density increased by a mean of 33.5% vs. baseline in the active group (p<0.0001), against 7.2% in the placebo group (not statistically significant). The twelve-week endpoint corresponds to completing all three courses in this pack. Report: Abich REL/0504/2026, issued 02 March 2026.
Funding disclosure: this twelve-week efficacy study was sponsored by Core Biogenesis, the supplier of the active ingredient. The full methodology and results are published so the funding source can be weighed against the data.
Composition (per bottle)
- FGF·2: 100 ng/mL (0.0005%)
- FGF·7: 500 ng/mL (0.0025%)
- Carrier: Camelina sativa oleosome
- Humectants: glycerin 4%, trehalose 3%
- Preservative system: propanediol, 1,2-hexanediol, caprylhydroxamic acid (≤ 2% total)
- Texture: xanthan gum 0.3%
- pH: 5.8 ± 0.2 at 25°C
Not in the formulation: fragrance, silicones, animal-derived inputs.
Storage
Refrigeration is recommended. Storing at 2 to 8 °C best preserves protein activity, so it is the conservative choice rather than a strict requirement; the formulation tolerates room temperature without harm. Do not freeze.
How to use
Twice daily, morning and evening, dispense two pumps directly to a clean, towel-dried scalp. Massage for thirty seconds. Absorbs in sixty. One bottle per four-week course; three courses complete the twelve-week protocol.
Manufactured in the United States under ISO 22716. A hair-density research program.