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12 weeks. Same woman. Same camera angle.
Individual results vary
The carrier system behind OF·27 delivers growth factors intact, straight to the follicle.
Independent Clinical Study
40 women, 12 weeks. Placebo-controlled study of the active, run by Abich S.r.l. in Italy.
Measured, Not Claimed
Hair density +33.5% at week 12, against +7.2% on placebo.
Study of the active, funded by its supplier. Individual results vary.
Made In The USA
Drug-free and fragrance-free. Made to ISO 22716 standards.
12-Week Results Guarantee
Results in 12 weeks or your money back. Photo at the start and at week 12.
Your Hair Profile
Before we show you your result, let’s make sure we’ve got this right.
Your worst spot
Your part line
And you’re noticing
More shedding
You noticed hair loss
One to two years ago
You’re in
Menopause
You’ve already tried
—
What you want
Less shedding, regrowth, and thickness
Your result is built from these answers. Change anything that isn’t right.
growth phase is significantly shortened
A shorter growth phase means more shedding and less fullness. The good news is that for the first time there are actives shown to extend it.
More Shedding
Visible sign #1
Normally a hair grows for three to six years, then sheds. One shed, every few years, from each follicle.
Estrogen is what kept that phase long. When it drops, the phase gets cut short — and in women losing their hair, researchers have found hairs finishing the whole cycle in under six months.
So the same follicle that used to shed once every four years is now shedding eight times in the same four years.
Source: Dr. Rachel Thornton · Biotech Researcher, Hair & Scalp Science
Less Coverage
Visible sign #2
Every hair that sheds leaves a gap. The follicle sits empty for a while before the next one starts.
Run that eight times as often and far more of your follicles are sitting empty at any given moment. In women losing their hair, researchers measured half as much hair actually growing as in women who weren’t.
Source: Dr. Rachel Thornton · Biotech Researcher, Hair & Scalp Science
Less Thickness
Visible sign #3
The growing phase is also when the strand gets built. Less time building means less strand — so every hair comes back finer than the one it replaced, and it happens again each time around.
Researchers measured the hair of 1,099 women and found strand thickness peaks in your early forties and falls from there. It’s the thick ones you lose most of, which is why your ponytail feels thinner in your hand.
Source: Robbins et al., British Journal of Dermatology, 2012 (1,099 women with self-perceived hair loss)
This is an estimate based on your answers, not a medical diagnosis.
Built by a biotech researcher in hair & scalp scienceHere’s what the clinical study
measured in women
The active in OF·27 was tested in an independent, placebo-controlled study of 40 women with diffuse shedding, run by Abich S.r.l. Here is what it measured. A study in men is in planning.
Study of the active, not the finished formula. Individual results vary.
Independently TestedTested on 40 women with diffuse shedding.
Measured at week 12
+33.5% hair density at week 12, in the study of the active.
Before
AfterRun by Abich S.r.l., an independent lab, on the active in OF·27. Funded by the active’s supplier.
20 women used the active and 20 used a placebo. Measured with phototrichogram, hair density rose 33.5% at week 12, against 7.2% on placebo.
Hair thickness also rose, by 10.6% at week 12 compared with the start.
More density and thicker strands are what make a part look narrower and a ponytail feel fuller.
The active in OF·27, tested in 40 women with diffuse shedding.
+17.0% growing-to-resting hair ratio.
Before
AfterFGF-2 is the growth factor in OF·27. In the study, the ratio of growing to resting hairs was 17.0% higher than in the placebo group.
Hairs spend most of their life in the growth phase, so more of them growing at once is what builds fullness over time.
We have no data comparing it to other treatments, and the study ran 12 weeks, so we can’t say what happens after that.
FGF-2, tested in 40 women: more hairs in the growth phase than on placebo.
95% of women on the active said their hair felt stronger.
Before
AfterThe oleosome carrier is how the growth factor reaches the follicle intact, instead of staying on the surface.
95% of the women on the active said their hair felt stronger and healthier, against 40% on placebo. In 90%, investigators saw a visible change in density. Self-assessment and photo rating, active arm, day 84.
The oleosome carrier: a natural lipid shell that protects the growth factor on its way to the follicle.
Study of the active in 40 women, funded by its supplier. Individual results vary.
Built by a biotech researcher in hair & scalp scienceBuilt around
one growth factor
Many hair products aim at hair loss in general. OF·27 is built around one thing: supporting the growth phase.
Built For The
Root Cause
OF·27 is a leave-on serum. One pump a night goes straight onto the scalp, where hair grows from.
It is built around FGF-2, the growth factor studied in the Abich trial, carried in oleosomes so it reaches the follicle intact.
Oleosome
Delivery
The part of the follicle that controls hair growth sits below the surface, so delivery matters.
Ours is carried in oleosomes, a natural lipid shell that forms inside Camelina sativa seeds, so it can reach the follicle intact.
Tested Against
Placebo
The active in OF·27 was tested in an independent, placebo-controlled study.
40 women, 12 weeks, half of them on placebo. Hair was measured by phototrichogram. It is a study of the active, not the finished formula, and it was funded by the active’s supplier.
Formulated For
Scalp Comfort.
One pump nightly, on the scalp. Leave it on.
Drug-free and fragrance-free. A cosmetic serum, not a prescription product.
Loved by thousandsWomen recommend OF·27
to their friends
Independent Clinical Study
+33.5% hair density at week 12 vs +7.2% on placebo. 40 women, placebo-controlled, run by Abich S.r.l. in Italy.
Study of the active, funded by its supplier. Individual results vary.
The change is night and day
I took photographs before starting and again at the end, and side by side the change is night and day. My parting looks narrower, the scalp is less visible, and the hair along the front looks fuller. It didn’t happen overnight, but it’s far more noticeable than I ever expected. Thank you, OF·27.
My hair looking like mine again
I’m 62, wasn’t expecting a miracle. But by week 8 the top of my head stopped catching the light the way it used to, and my hairdresser noticed new growth around the crown before I said a word. My hair looking like mine again.
It shocked me how well it worked
I was losing so much hair in the shower I dreaded washing it. I didn’t expect much, but honestly it shocked me how well it worked on me. It’s light, absorbs fast, and doesn’t leave my hands greasy, so it was easy to do every night. I could see finer new hairs coming in along my hairline within the first month, and by week 12 the shedding had calmed right down. It built up over time, but it clearly works.
Results in 12 weeks
or your money back
The study of the active measured results at week 12: a higher growing-to-resting hair ratio and higher hair density than placebo.
Results in 12 weeks or your money back. Email a starting photo within 7 days of delivery, then one at week 12. No visible difference? You get your money back. Full conditions on the product page.
All it asks for is one pump before bed. Straight onto the scalp, leave it on. Drug-free, nothing swallowed, nothing prescribed.
The study of the active ran 12 weeks, so we suggest a 12-week nightly routine.
Built for hair loss on a GLP-1Your GLP-1 hair profile is ready
What you achieved
Down 20–40 lbs. You earned every one of them.
What it’s costing you
Your part. Wider, and you know which way to flip it.
What it doesn’t have to cost
Any of it.
You don’t have to trade one for the other.
The active in OF·27 was tested for 12 weeks in 40 women. Here is how it fits your goal of less shedding and real regrowth.
— Dr. Rachel Thornton
Dr. Rachel Thornton / Biotech Researcher, Hair & Scalp ScienceYour GLP-1 may have pushed
more hair out of growing
Anagen-to-telogen ratio
less shedding Balance
tipping More shedding,
less growing
6–12 months ago — You started
Hair is only ever doing one of two things: anagen, growing without interruption, or telogen, where it stops growing and sheds out later.
Rapid weight loss can shift the balance — hair that should have stayed in anagen moves into telogen instead. A healthy scalp holds most of its hair in anagen. When the balance tips, that share falls.
3–6 months ago — You noticed it
The first hairs that shifted finished telogen and let go — that’s what showed up in your brush and your shower drain. But that was only the first batch. You were still on your GLP-1, so more kept shifting behind them.
3–6 months ago — You came off
Most women are told the shedding settles once the GLP-1 is out. That’s true of what hadn’t shifted yet — nothing new gets pushed into telogen after you stop.
It isn’t true of what already had shifted.
Today — It’s visible
Every month on your GLP-1, another batch moves into telogen and sheds out. And the follicles they leave behind stay empty — nothing’s pushing them back into anagen while you’re still on it.
So it builds both ways. Which is why your part typically keeps widening — more falling out each month, and less coming back to fill what already went.
Ahead — What the research shows
A follicle can sit in telogen a while and still come back. Past a point, it stops re-entering anagen at all.
You said you’re staying on your GLP-1 as long as it takes. That’s the right call for your health — but it keeps shifting hair into telogen the whole time, and more of it crosses over while it does — and the longer it runs, the more of it there is.
This timeline is an estimate based on your answers, not a medical assessment. Individual experiences vary.
Built by a biotech researcher in hair & scalp scienceYour match: five actives that
support the growth phase
BeforeAfter
FGF-2
Hair Cycle ActiveA growth factor studied for how long hair keeps growing. In the Abich study of the active, the ratio of growing to resting hairs was 17.0% higher than on placebo.
Oleosome carrier
DeliveryA natural lipid shell that carries the growth factor to the follicle intact. In the Abich study of the active, hair density rose 33.5% at week 12, against 7.2% on placebo.
Niacinamide
Scalp SupportSupports a calm, well-moisturized scalp, the ground the follicle grows from.
Panthenol
Scalp SupportPanthenol (vitamin B5) helps keep the scalp moisturized and comfortable.
Adenosine
Scalp SupportAdenosine supports a calm scalp alongside niacinamide and panthenol.
Study of the active in 40 women, funded by its supplier. Individual results vary.
Tested by Abich S.r.l., ItalyTested on 40 women with diffuse shedding.
Measured at week 12
+33.5% hair density at week 12, in the study of the active.
BeforeAfterRun by Abich S.r.l., an independent lab, on the active in OF·27. Funded by the active’s supplier.
40 women with diffuse shedding, half of them on placebo. Measured with phototrichogram, density rose 33.5% on the active against 7.2% on placebo.
95% said their hair felt stronger and healthier (placebo group: 40%). In 90%, investigators saw a visible change in density. Self-assessment and photo rating, active arm, day 84.
Dr. Rachel Thornton
Biotech Researcher, Hair & Scalp Science
“The carrier system behind OF·27 delivers growth factors intact, straight to the follicle.”
+17.0% growing-to-resting hair ratio.
BeforeAfterThe study tested the growth-factor active on its own, before the finished formula.
Density: hair density rose 33.5% at week 12, against 7.2% on placebo.
Thickness: hair shaft diameter rose 10.6% at week 12 compared with the start.
Study: 20 women on the active and 20 on placebo, for 12 weeks.
We have no data comparing it to other treatments, and the study ran 12 weeks, so we can’t say what happens after that.
Study of the active in 40 women, funded by its supplier. Individual results vary.
Loved by thousands
Women who tried it,
at week 12
Megan L.
It shocked me how well it worked
I was losing so much hair in the shower I dreaded washing it.
- I didn’t expect much, but honestly it shocked me how well it worked on me.
- It’s light, absorbs fast, and doesn’t leave my hands greasy, so it was easy to do every night.
- I could see finer new hairs coming in along my hairline within the first month.
- By week 12 the shedding had calmed right down.
- It built up over time, but it clearly works.
- Personal experience, not study data.
Verified customer, week 12.
Catherine M.
Nothing like the treatments I’ve tried
This feels nothing like the treatments I’ve tried before. My hair looks fuller and thicker for the first time in years.
…and more customer stories on the product page
Results in 12 weeks
or your money back
The study of the active measured results at week 12: a higher growing-to-resting hair ratio and higher hair density than placebo.
Results in 12 weeks or your money back. Email a starting photo within 7 days of delivery, then one at week 12. No visible difference? You get your money back. Full conditions on the product page.
All it asks for is one pump on the scalp before bed. Drug-free, nothing swallowed, nothing prescribed.
The study of the active ran 12 weeks, so we suggest a 12-week nightly routine.